The dawn of a nutritional science
The relevant role of metabolomics is being recognized in nutrition studies. Thus, the paradigm of epidemiology-based nutrition counsel can be switched towards individual-based nutrition. In this sense, a very recent and comprehensive review illustrates the potential of the so-called nutritional metabolomics or nutrimetabolomics (Mol Nutr Food Res. 2018 Sep 3:e1800384. doi:10.1002/mnfr.201800384.). In this review, the authors offer a very detailed description of methodologies employed in nutrimetabolomics, towards quality system-based generation of scientific evidence. This is based in the European initiative Food Biomarker Alliance, a program funded by European Joint Programming Initiative «A Healthy Diet for a Healthy Life» (JPI HDL) and will help Metabolomics and Nutritional scientist to harmonize this relevant field. Among other, relevant factors such as study designs, sample characteristics and preanalytical processing, chromatography, data acquisition visualization and analyse, as well as guidelines for evaluating health status are presented. For instance, they discuss the usefulness of specific metabolites in handling disease risks (such as insulin resistance) in comparison to more classical markers. Further, it is stated that «.Despite this limitation, patterns or signatures of metabolites that come with different types of diets comprising variable quantities of food of plant or animal origin will help epidemiologists to improve data quality when assessing the diet-health relationship.».
At Biomeb we do our best to keep an updated database of this relevant science. Most of the key points raised in this review are well known by Biomeb analytical scientist, therefore helping end-users to have a product with the highest’s standards of quality. Further, as an ever-evolving science, the individual track of metabolome signatures will help end-users to get a personalized view of their metabolism, therefore allowing science-based choices in lifestyle changes towards health promotion.